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HESI RN · HESI Pharmacology · Principles of Pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which of the following terms best defines the cimetidine-diazepam interaction in the 46-year-old woman?

A. Synergism

B. Potentiation

C. Additive

D. Antagonism

Expert Explanatory Rationale

Correct Answer: Potentiation

Question 2 of 5

A 45-year-old woman recently diagnosed with lupus erythematosus started a treatment with a synthetic steroid. Which of the following is the most likely time lapse expected between receptor activation and therapeutic response?

A. Few milliseconds

B. Few seconds

C. Few minutes

D. One or 2 hours

Expert Explanatory Rationale

Correct Answer: One or 2 hours

Question 3 of 5

Phase I oxidative-reductive processes of drug metabolism require certain nutritional elements. Which of the following would reduce or inhibit this process?

A. Protein malnutrition

B. Iron deficiency anemia

C. Both A and B

D. Neither A nor B

Expert Explanatory Rationale

Correct Answer: Both A and B

Question 4 of 5

Which of the following permeation processes mediated the man's intestinal absorption of ethanol after drinking alcoholic beverages?

A. Aqueous diffusion

B. Bulk flow transport

C. Facilitated diffusion

D. Active transport

Expert Explanatory Rationale

Correct Answer: Aqueous diffusion

Question 5 of 5

What is the mechanism that allows mannitol to produce diuresis?

A. Competes with aldosterone for cellular receptor sites

B. Inhibits the reabsorption of sodium and chloride in the loop of Henle

C. Interferes with absorption of sodium ions across the distal renal tubule

D. Increases the osmolarity of plasma and pulls water out of the tissues into the bloodstream

Expert Explanatory Rationale

Correct Answer: Increases the osmolarity of plasma and pulls water out of the tissues into the bloodstream

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