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HESI RN · HESI Pharmacology · Pharmacology Across the Lifespan ATI

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

An 18-year-old man is brought to the emergency department by a friend after smoking crack cocaine because he was 'acting funny.' His temperature is 38°C (100.4°F), pulse is 110 beats/minute, and he appears agitated. What is the action of cocaine on sympathetic nerves?

A. Increase norepinephrine synthesis
B. Inhibition of catechol-O-methyltransferase (COMT)
C. Inhibition of monoamine oxidase (MAO)
D. Inhibition of norepinephrine reuptake

Expert Explanatory Rationale

Correct Answer: Inhibition of norepinephrine reuptake

Question 2 of 5

A 39-year-old man with recurrent fungal infections is seen by his primary care physician. Consideration is given to prescribing terbinafine for this patient. Although the medication can be given without regard to meals, a possible problem with this medication can be which of the following?

A. Accumulation in tissues
B. Nephrotoxicity
C. Neuromuscular blockade
D. Ototoxicity

Expert Explanatory Rationale

Correct Answer: Accumulation in tissues

Question 3 of 5

The “7 Rights of medication administration are the right individual, medication, dose:

A. time, color, place, size.
B. size, time, color, hand.
C. time, route, consistency, MAR.
D. time, size, color, MAR.

Expert Explanatory Rationale

Correct Answer: size, time, color, hand.

Question 4 of 5

Characteristics of pilocarpine include all of the following EXCEPT:

A. It is a tertiary amine alkaloid
B. It causes miosis and a decrease in intraocular pressure
C. Assess a decrease in increased risk of activity of gut
D. It is useful in the treatment of glaucoma

Expert Explanatory Rationale

Correct Answer: Assess a decrease in increased risk of activity of gut

Question 5 of 5

A 65-year-old male with type 2 diabetes is prescribed metformin. Metformin works primarily by:

A. Increasing insulin secretion from the pancreas
B. Improving insulin sensitivity in peripheral tissues
C. Inhibiting the absorption of glucose in the intestines
D. Increasing renal glucose excretion

Expert Explanatory Rationale

Correct Answer: Improving insulin sensitivity in peripheral tissues

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