Complete Question Bank

HESI RN · HESI Pharmacology · Pharmacological Lifespan Treatment

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Methotrexate is:

A. A purine antagonist

B. A folic acid antagonist

C. An antibiotic

D. An alkylating agent

Correct Answer: A folic acid antagonist

Question 2 of 5

Currently used oral hypoglycemic biguanides include the following, EXCEPT:

A. Repaglinide (Prandin)

B. Metformin

C. Phenformine

D. Glipizide

Correct Answer: Repaglinide (Prandin)

Question 3 of 5

A 60-year-old male with diabetes is prescribed metformin. Metformin works by:

A. Increasing insulin secretion from the pancreas

B. Improving insulin sensitivity in peripheral tissues

C. Inhibiting the absorption of glucose in the intestines

D. Increasing renal glucose excretion

Correct Answer: Improving insulin sensitivity in peripheral tissues

Question 4 of 5

The volume of distribution for a drug that is completely retained in the vascular compartment would be:

A. High

B. Low

C. Unchanged

D. Cannot be determined

Correct Answer: Low

Question 5 of 5

How the medication produces the desired therapeutic effect

A. Teratogenic effect

B. Mechanism of action

C. Therapeutic index

D. Half-life

Correct Answer: Mechanism of action

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