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HESI RN · HESI Pharmacology · Drugs for immune system

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which one of the following statements about 'one daily' dosing with aminoglycosides is false?

A. It is convenient for outpatient therapy

B. Adjustment of dosage is less important in renal insufficiency

C. Less nursing time is required

D. It is often less toxic than conventional (multiple) dosing regimens

Expert Explanatory Rationale

Correct Answer: Adjustment of dosage is less important in renal insufficiency

Question 2 of 5

The drug of choice for treatment of methicillin-resistant Staphylococcus aureus infection is

A. Cloxacillin

B. Vancomycin

C. Erythromycin

D. Amikacin

Expert Explanatory Rationale

Correct Answer: Vancomycin

Question 3 of 5

Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellulare (MAI)?

A. Vancomycin

B. Clarithromycin

C. Erythromycin base

D. Troleandomycin

Expert Explanatory Rationale

Correct Answer: Clarithromycin

Question 4 of 5

The most important mechanism by which gram-negative bacilli acquire chloramphenicol resistance is

A. Decreased permeability into the bacterial cell

B. Acquisition of a plasmid encoded for chloramphenicol acetyl transferase

C. Lowered affinity of the bacterial ribosome for chloramphenicol

D. Switching over from ribosomal to mitochondrial protein synthesis

Expert Explanatory Rationale

Correct Answer: Acquisition of a plasmid encoded for chloramphenicol acetyl transferase

Question 5 of 5

Bleomycin is used in most effective drug combination regimen for the chemotherapy of testicular carcinoma. Which one of the following statements about the drug is accurate?

A. Acts mainly in the M phase of the cell cycle

B. Derived from the bark of yew trees

C. Myelosuppression is dose-limiting

D. Pulmonary infiltrates and fibrosis may occur

Expert Explanatory Rationale

Correct Answer: Pulmonary infiltrates and fibrosis may occur

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