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HESI RN · HESI Pharmacology · Diabetes drugs

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Sulfonylureas are more commonly used than biguanides as oral hypoglycaemics because

A. Biguanides are less efficacious

B. Sulfonylureas lower blood sugar in both IDDM and NIDDM patients

C. Sulfonylureas also aid weight reduction in obese diabetics

D. Biguanides are prone to precipitate ketoacidosis

Expert Explanatory Rationale

Correct Answer: Biguanides are less efficacious

Question 2 of 5

The antidiabetic agent most likely to cause lactic acidosis is

A. Chlorpropamide

B. Phenformin

C. Glipizide

D. Metformin

Expert Explanatory Rationale

Correct Answer: Phenformin

Question 3 of 5

Which of the following is true of acarbose?

A. It reduces absorption of glucose from intestines

B. It produces hypoglycaemia in normal as well as diabetic subjects

C. It limits postprandial hyperglycaemia in diabetes

D. It raises circulating insulin levels

Expert Explanatory Rationale

Correct Answer: It limits postprandial hyperglycaemia in diabetes

Question 4 of 5

The insulin receptor is a

A. Ion channel regulating receptor

B. Tyrosine protein kinase receptor

C. G-protein coupled receptor

D. None of these

Expert Explanatory Rationale

Correct Answer: Tyrosine protein kinase receptor

Question 5 of 5

A mass of adipose tissue that develops at the injection site is usually due to the patients neglect in rotating the insulin injection site. This is known as

A. Lipoatrophy

B. Hypertrophic degenerative adiposity

C. Lipohypertrophy

D. Atrophic skin lesion

Expert Explanatory Rationale

Correct Answer: Lipohypertrophy

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