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HESI RN · HESI Pharmacology · Ch 30 principles of pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

All the following result in diarrhea except:

A. Misoprostol

B. Metoclopramide.

C. Magnesium containing antacids.

D. Sucralfate

Expert Explanatory Rationale

Correct Answer: Sucralfate

Question 2 of 5

Adverse effects associated with rifampicin include:

A. Hepatitis and cholestatic jaundice

B. Peripheral neuropathy

C. Convulsions

D. Influenza-like symptoms

Expert Explanatory Rationale

Correct Answer: Hepatitis and cholestatic jaundice

Question 3 of 5

Cross MATCH each drug to its specific adverse effect: Bisacodyl

A. Intestinal obstruction if not taken with plenty of fluids

B. Mutagenic.

C. Purple coloration of urine

D. Flatulence & aggravation of diabetes

Expert Explanatory Rationale

Correct Answer: Purple coloration of urine

Question 4 of 5

With regard to distribution of a drug from the blood into tissues

A. Blood flow to the tissue is an important determinant

B. Solubility of the drug in the tissue is an important determinant

C. Concentration of the drug in the blood is an important determinant

D. Size (volume) of the tissue is an important determinant

Expert Explanatory Rationale

Correct Answer: Blood flow to the tissue is an important determinant

Question 5 of 5

The P-glycoprotein is a multidrug transmembrane transporter protein that transports medications across cell membranes. Functions of this protein include

A. Pumping drugs into the urine for excretion

B. Transport of drugs into liver hepatocytes

C. Transport of drugs into fetal circulation for fetal treatment

D. Transport of drugs from the intestinal lumen to the circulation

Expert Explanatory Rationale

Correct Answer: Transport of drugs into liver hepatocytes

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