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HESI RN · HESI Pharmacology · ABVD chemotherapy drugs

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which one of the following is least likely to be a mechanism of cancer cell resistance to antineoplastic drugs?

A. Change in properties of a target enzyme
B. Decreased activity of activating enzymes
C. Increase in drug-metabolizing cytochrome P450
D. Increase in DNA repair

Expert Explanatory Rationale

Correct Answer: Decreased activity of activating enzymes

Question 2 of 5

An antimicrobial that is better to be avoided in patients with myasthenia gravis?

A. Gentamycin
B. Rifampicin
C. Ampicillin
D. Tetracycline

Expert Explanatory Rationale

Correct Answer: Gentamycin

Question 3 of 5

A 54-year-old man with tuberculosis is maintained on a multidrug regimen including cycloserine. He complains of intermittent chest pressure and dyspnea but this does not limit his daily activities. On a cellular level, which of the following amino acids is blocked by this agent?

A. D-alanine
B. D-aspartate
C. D-glutamate
D. Para-aminobenzoate

Expert Explanatory Rationale

Correct Answer: D-alanine

Question 4 of 5

Which of the following statements is CORRECT:

A. Tamoxifen blocks hypothalamic estrogen receptors
B. Finasteride is used in prostatic hyperplasia as it relaxes bladder sphincter
C. Raloxifene may increase risk of breast cancer
D. Urofollitropin & minotropins stimulate ovulation in infertility

Expert Explanatory Rationale

Correct Answer: Urofollitropin & minotropins stimulate ovulation in infertility

Question 5 of 5

Ticarcillin is relatively unique among all the penicillins because it poses a greater risk of a relatively unique side effect or adverse response. Which of the following best summarizes what that unique unwanted effect is?

A. Acute renal failure
B. Bronchoconstriction, bronchospasm, asthma
C. Fever, arthralgia, anc other signs of a lupus-like syndrome
D. Hypertension, hypervolemia, and bleeding

Expert Explanatory Rationale

Correct Answer: Hypertension, hypervolemia, and bleeding

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