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HESI LPN · HESI LPN Pharmacology · LPN Lifespan Pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which of the following oral hypoglycaemic drugs stimulates both synthesis and release of insulin from beta islet cells:

A. Glibenclamide
B. Phenformin
C. Buformine
D. Metformin

Expert Explanatory Rationale

Correct Answer: Glibenclamide

Question 2 of 5

Which competitive neuromuscular blocking agent could be used in patients with renal failure?

A. Atracurium
B. Succinylcholine
C. Pipecuronium
D. Doxacurium

Expert Explanatory Rationale

Correct Answer: Atracurium

Question 3 of 5

Tick the mechanism of Metoclopramide antiemetic action:

A. H1 and H2-receptor blocking effect
B. M-cholinoreceptor stimulating effect
C. D2-dopamine and 5-HT3-serotonin receptor blocking effect
D. M-cholinoblocking effect

Expert Explanatory Rationale

Correct Answer: D2-dopamine and 5-HT3-serotonin receptor blocking effect

Question 4 of 5

The physician has prescribed a brand name drug for the client. The client tells the nurse that the medication is too expensive. What is the best plan by the nurse?

A. Help the client receive free medicine through a 'patient assistance' program.
B. Ask the physician if a cheaper brand name drug may be substituted.
C. Ask the physician if a generic drug may be substituted.
D. Maintain the client on samples of the brand name drug from the physician’s office.

Expert Explanatory Rationale

Correct Answer: Ask the physician if a generic drug may be substituted.

Question 5 of 5

The increase of second messengers’ (cAMP, cGMP, Ca²⁺ etc.) concentration leads to:

A. Inhibition of intracellular protein kinases and protein phosphorylation
B. Proteinkinases activation and protein phosphorylation
C. Blocking of interaction between a receptor and an effector
D. Antagonism with endogenous ligands

Expert Explanatory Rationale

Correct Answer: Proteinkinases activation and protein phosphorylation

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