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HESI LPN · HESI LPN Pharmacology · LPN Drugs and the Peripheral Nervous System

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which one of the following drugs, when used chronically, is associated with the development of bone pain and mineralization defects such as osteomalacia?

A. Calcitonin
B. Dihydrotachysterol
C. Ergocalciferol
D. Etidronate

Expert Explanatory Rationale

Correct Answer: Etidronate

Question 2 of 5

A patient with a recent drug poisoning is transported to the emergency department. The physician orders (correctly, in this case) administration of pralidoxime as part of the comprehensive emergency treatment plan. Which one of the following best describes who the patient was?

A. A 13-year-old boy who took an overdose of amphetamine for his ADD/ADHD
B. A 43-year-old who took an overdose of neostigmine, prescribed for her myasthenia gravis, in a suicide attempt
C. A 6-year-old who got into the family medicine cabinet and took 10 'adult doses' of her dad's prazosin
D. A farm/field worker accidentally doused with insecticide from an overflying cropduster plane

Expert Explanatory Rationale

Correct Answer: A farm/field worker accidentally doused with insecticide from an overflying cropduster plane

Question 3 of 5

The fall in blood pressure caused by d-tubocurarine is due to

A. Reduced venous return
B. Ganglionic blockade
C. Histamine release
D. All of the above

Expert Explanatory Rationale

Correct Answer: All of the above

Question 4 of 5

Increased heart rate and dilated pupils are associated with the activation of the:

A. Sympathetic nervous system
B. Parasympathetic nervous system
C. Both systems
D. None of the above

Expert Explanatory Rationale

Correct Answer: Sympathetic nervous system

Question 5 of 5

A morbidly obese person visits the local bariatric (weight loss) clinic king a pill that will help shed weight. The physician prescribes dextroamphetamine. In addition to causing its expected centrally mediated anorexigenic (appetite-suppressant) effects it causes a host of peripheral adrenergic effects that, for some patients, can prove fatal. The main mechanism by which dextroamphetamine or amphetamines in general, cause their peripheral autonomic effects is

A. Activates MAO
B. Blocks NE reuptake via the amine pump/transporter
C. Displaces, releases, intraneuronal NE
D. Enhances NE synthesis, leading to massive neurotransmitter overproduction

Expert Explanatory Rationale

Correct Answer: Displaces, releases, intraneuronal NE

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