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HESI LPN · HESI LPN Pharmacology · HESI Pharmacology CNS Drugs Classification

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

A 48-year-old man with schizophrenia on thioridazine for 20 years develops bilateral facial and jaw movements and rhythmic motions of his tongue. Physical examination of the heart, lungs, and abdomen are unremarkable. What is the most likely aberration on a neurotransmitter level?

A. Acetylcholine
B. Dopamine
C. Epinephrine
D. Norepinephrine

Expert Explanatory Rationale

Correct Answer: Dopamine

Question 2 of 5

α-Glucosidase, an enzyme that is inhibited by acarbose, is responsible for:

A. Untwisting of DNA strands during cancer cell replication
B. Resistance to cephalosporins
C. Carbohydrate digestion in and absorption from the gut
D. Toxicity caused by methotrexate

Expert Explanatory Rationale

Correct Answer: Carbohydrate digestion in and absorption from the gut

Question 3 of 5

A novel medication to treat gastric motility disorders will act at the terminal step in the synthesis/breakdown of acetylcholine. Which of the following is the terminal step in the synthesis and release of acetylcholine?

A. Degradation
B. Release of neurotransmitter
C. Recycling of choline
D. Synthesis

Expert Explanatory Rationale

Correct Answer: Release of neurotransmitter

Question 4 of 5

A 28-year-old man is hospitalized on the trauma service with multiple organ system failure after sustaining multiple fractures and internal injuries. His most recent CT scan of the abdomen does not reveal any visceral organ injury. He is currently on an intravenous epinephrine drip to maintain his blood pressure and heart rate. His most recent laboratory studies reveal a blood glucose level of 425 mg/dL. What is the most likely explanation of this finding?

A. Hepatic glycogenolysis
B. Hepatic gluconeogenesis
C. Pancreatic failure
D. Pancreatic infarct from trauma

Expert Explanatory Rationale

Correct Answer: Hepatic glycogenolysis

Question 5 of 5

Which of the following is a sign of deep anesthesia?

A. Appearance of tears in eyes
B. Resistance to passive inflation of lungs
C. Fall in blood pressure
D. Patient makes swallowing movements

Expert Explanatory Rationale

Correct Answer: Fall in blood pressure

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