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HESI LPN · HESI LPN Pharmacology · HESI Pharmacology Across the Lifespan ATI

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which of the following is true about the blood-brain barrier?

A. Endothelial cells of the blood-brain barrier have slit junctions.
B. Ionized or polar drugs can cross the blood-brain barrier easily.
C. Drugs cannot cross the blood-brain barrier through specific transporters.
D. Lipid-soluble drugs readily cross the blood-brain barrier.

Expert Explanatory Rationale

Correct Answer: Lipid-soluble drugs readily cross the blood-brain barrier.

Question 2 of 5

Which of the following vitamins improves megaloblastic anemia but does not protect the neurological manifestations of pernicious anemia?

A. Vitamin B12
B. Vitamin BС
C. Vitamin PP
D. Vitamin D

Expert Explanatory Rationale

Correct Answer: Vitamin BС

Question 3 of 5

A48-year-old woman suffering from allergic urticaria started a treatment with loratadine. The decreased synthesis of which of the following substances most likely mediated the therapeutic effect of the drug in the patient's disease?

A. Cyclic adenosine monophosphate (cAMP)
B. Cyclic guanosine monophosphate (cGMP)
C. Inositol triphosphate
D. Cyclooxygenase-1

Expert Explanatory Rationale

Correct Answer: Inositol triphosphate

Question 4 of 5

Primary hypothyroidism may be suspected in what scenario?

A. If T3 high and T4 low
B. If TSH high
C. If TSH low
D. If T3 high

Expert Explanatory Rationale

Correct Answer: If TSH high

Question 5 of 5

Tick the drug for echinococcosis treatment:

A. Suramin
B. Mebendazole or Albendazole
C. Piperazine
D. Iodoquinol

Expert Explanatory Rationale

Correct Answer: Mebendazole or Albendazole

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