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HESI LPN · HESI LPN Pharmacology · HESI NCLEX questions on chemotherapy drugs

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

If a drug is active against the preerythrocytic stage of the malarial parasite it will be useful as a

A. Suppressive prophylactic
B. Causal prophylactic
C. Clinical curative
D. Radical curative

Expert Explanatory Rationale

Correct Answer: Causal prophylactic

Question 2 of 5

The drug of choice for Kala Azar is

A. Pentamidine
B. Amphotericin B
C. Sodium stibogluconate
D. Ketoconazole

Expert Explanatory Rationale

Correct Answer: Sodium stibogluconate

Question 3 of 5

A 24-year-old primigravid woman’s water breaks at 39 weeks gestation. Twenty-four hours later, she is having regular contractions 3 min apart. Her labor lasts 8 h. At the hospital, she gives birth to a baby boy, who initially appeared healthy. Within the next 12 h, the baby boy begins to have temperature fluctuations, difficulty breathing, and reduced movements. You suspect neonatal sepsis, so IV ampicillin is started. Which additional antibiotic could be given simultaneously to have a synergistic effect in controlling this infection?

A. Amoxicillin
B. Cephalexin
C. Gentamicin
D. Penicillin G

Expert Explanatory Rationale

Correct Answer: Gentamicin

Question 4 of 5

A 73-year-old man with overwhelming sepsis requiring intravenous fluid support, pressors, and antibiotics is now beginning to improve clinically. The rationale against the use of a bacteriostatic antibiotic in this patient includes which of the following?

A. Arrest growth of bacteria
B. Cause cell death of pathogens
C. Removal of viable organisms
D. Requirement for lower doses of medication

Expert Explanatory Rationale

Correct Answer: Removal of viable organisms

Question 5 of 5

The following is true of quinine

A. It has a longer elimination half-life than chloroquine
B. It is not to be used for prophylaxis of malaria
C. It is not active against P. vivax
D. It should not be used along with sulfapyrimethamine

Expert Explanatory Rationale

Correct Answer: It is not to be used for prophylaxis of malaria

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