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HESI LPN · HESI LPN Pharmacology · HESI Drugs and immune system

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which of the following statements about vancomycin is accurate?

A. It is bacteriostatic

B. It binds to PBPs

C. It is not susceptible to penicillinase

D. It has the advantage of oral bioavailability

Expert Explanatory Rationale

Correct Answer: It is not susceptible to penicillinase

Question 2 of 5

A 36-year-old woman recently treated for leukemia is admitted to hospital with malaise, chills and high fever. Gram stain of blood reveals the presence of gram-negative bacilli. The initial diagnosis is bacteremia and parenteral antibiotics are indicated. The records of the patient reveal that she had a severe urticarial rash, hypotension, and respiratory difficulty following oral penicillin V about 6 months ago. The most appropriate drug regimen for empiric treatment is

A. Ampicillin plus sulbactam

B. Aztreonam

C. Cefazolin

D. Imipenem plus cilastatin

Expert Explanatory Rationale

Correct Answer: Aztreonam

Question 3 of 5

Which one of the following antibiotics is likely to be most effective agent in the treatment of an infection due to enterococci if used in conjunction with penicillin G?

A. Amikacin

B. Gentamicin

C. Netilmicin

D. Streptomycin

Expert Explanatory Rationale

Correct Answer: Gentamicin

Question 4 of 5

Select the antibiotic with a high therapeutic index

A. Streptomycin

B. Doxy

C. Cephalexin

D. Polymyxin B

Expert Explanatory Rationale

Correct Answer: Cephalexin

Question 5 of 5

Sulfamethoxypyridazine and other related long-acting sulfonamides have now gone into disuse because

A. They have produced serious cutaneous reactions

B. They have produced high incidence of crystalluria

C. They interact with many drugs

D. They do not penetrate blood-brain barrier

Expert Explanatory Rationale

Correct Answer: They have produced serious cutaneous reactions