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HESI LPN · HESI LPN Pharmacology · HESI CNS Drugs Pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because

A. It has low efficacy

B. It produces first dose hypotension

C. Used alone, its effective doses produce intolerable side effects

D. Its therapeutic effect takes long time to develop

Expert Explanatory Rationale

Correct Answer: Used alone, its effective doses produce intolerable side effects

Question 2 of 5

A 43-year-old man who is a heroin addict is placed on methadone therapy to wean him off of heroin. Which of the following statements is true regarding the pharmacology of this agent?

A. Best absorbed following intravenous administration

B. Biotransformed in the liver and excreted in urine

C. Lipophilic causing accumulation in tissues

D. Metabolism dependent in single cytochromes in the liver

Expert Explanatory Rationale

Correct Answer: Biotransformed in the liver and excreted in urine

Question 3 of 5

The inhalation anesthetic with the fastest onset of action is

A. Enflurane

B. Isoflurane

C. Nitrous oxide

D. Nitrogen dioxide

Expert Explanatory Rationale

Correct Answer: Nitrous oxide

Question 4 of 5

Which one of the following chemicals does not satisfy the criteria for a neurotransmitter role in the CNS?

A. Acetylcholine

B. Dopamine

C. Glycine

D. Nitric Oxide

Expert Explanatory Rationale

Correct Answer: Nitric Oxide

Question 5 of 5

Dale's vasomotor reversal phenomenon is exhibited by

A. Adrenaline

B. Noradrenaline

C. Isoprenaline

D. Both (a) and (b)

Expert Explanatory Rationale

Correct Answer: Adrenaline

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