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HESI LPN · HESI LPN Pharmacology · HESI Chapter 26 principles of pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

GERD may benefit from the following except:

A. Omeprazole
B. Ranitidine
C. Hyoscine butylbromide
D. Domperidone

Expert Explanatory Rationale

Correct Answer: Hyoscine butylbromide

Question 2 of 5

With regard to clinical trials of new drugs, which of the following is most correct?

A. Phase I involves the study of a small number of normal volunteers by highly trained clinical pharmacologists
B. Phase II involves the use of the new drug in a large number of patients (100-5000) who have the disease to be treated
C. Phase III involves the determination of the drug's therapeutic index by the cautious induction of toxicity
D. Chemical antagonist

Expert Explanatory Rationale

Correct Answer: Phase I involves the study of a small number of normal volunteers by highly trained clinical pharmacologists

Question 3 of 5

A medical student is involved in a summer research project evaluating the excitatory and inhibitory effects of five neurotransmitters. Following as choices are the five neurotransmitters and their excitatory and inhibitory status. Which of the following neurotransmitters is likely to be serotonin?

A. Neurotransmitter A; excitatory
B. Neurotransmitter B; excitatory
C. Neurotransmitter C; excitatory and inhibitory
D. Neurotransmitter D; inhibitory

Expert Explanatory Rationale

Correct Answer: Neurotransmitter C; excitatory and inhibitory

Question 4 of 5

Quinine sulfate:

A. Is the drug of choice in chloroquine-resistant falciparum malaria
B. Is available for intravenous and oral use
C. Is effective in eradicating the hepatic parasites in Plasmodium vivax malaria
D. Is contraindicated in renal failure

Expert Explanatory Rationale

Correct Answer: Is the drug of choice in chloroquine-resistant falciparum malaria

Question 5 of 5

Phenylephrine causes

A. Constriction of vessels in the nasal mucosa
B. Increased gastric secretion and motility
C. Increased skin temperature
D. Miosis

Expert Explanatory Rationale

Correct Answer: Constriction of vessels in the nasal mucosa

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