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HESI LPN · HESI LPN Pharmacology · HESI Cardiovascular Drugs Nursing Pharmacology

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

A patient prescribed alprazolam (Xanax) for symptoms of anxiety shares with the nurse that, 'I'm concerned about getting off this medication.' Upon which fact will the nurse base the response to the patient's concern?

A. Long elimination half-life will result in a manageable withdrawal treatment plan.
B. Rapid absorption and distribution to brain cells make withdrawal more difficult to manage.
C. Sensitivity of the mesencephalic reticular activating system makes addiction unlikely.
D. The combination of medication with an antidepressant often positively impacts withdrawal.

Expert Explanatory Rationale

Correct Answer: Rapid absorption and distribution to brain cells make withdrawal more difficult to manage.

Question 2 of 5

One advantage of gemfibrozil (Lopid) is that, in addition to lowering blood levels of most lipids, it raises the level of HDL cholesterol. This consideration is:

A. TRUE
B. FALSE
C. All
D. None

Expert Explanatory Rationale

Correct Answer: TRUE

Question 3 of 5

Which of the following statements concerning biotin functions are true:

A. Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems
B. Essential constituent of coenzyme A, the important coenzyme for acyl transfer in the TCA cycle and de novo fatty acid synthesis
C. An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable
D. Coenzyme for several reactions involving CO2 fixation into various compounds e.g. acetyl CoA to malonyl CoA (acetyl CoA carboxylase) – initial step in de novo fatty acid synthesis; propionyl CoA to methylmalonyl CoA (propionyl CoA carboxylase), pyruvate to oxaloacetate (pyruvate carboxylase)

Expert Explanatory Rationale

Correct Answer: Coenzyme for several reactions involving CO2 fixation into various compounds e.g. acetyl CoA to malonyl CoA (acetyl CoA carboxylase) – initial step in de novo fatty acid synthesis; propionyl CoA to methylmalonyl CoA (propionyl CoA carboxylase), pyruvate to oxaloacetate (pyruvate carboxylase)

Question 4 of 5

Agents,stimulating CNS are all of the following except:

A. Fluoxetine
B. Clozapine
C. Nootropil
D. Sydnocarb

Expert Explanatory Rationale

Correct Answer: Clozapine

Question 5 of 5

Tick the drug used as an oral anticoagulant:

A. Heparin
B. Daltreparin
C. Dicumarol
D. Enoxaparin

Expert Explanatory Rationale

Correct Answer: Dicumarol

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