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HESI LPN · HESI LPN Pharmacology · HESI Basic pharmacology principles

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Sodium bicarbonate has the following disadvantages except:

A. It causes rebound hyperacidity

B. It causes gastric distension

C. It has delayed onset of action

D. It may be dangerous in patients with heart failure

Correct Answer: It has delayed onset of action

Question 2 of 5

Used to describe drugs with identical areas under the curve (AUCs)

A. Systemic clearance (CLs)

B. Volume of distribution (Vd)

C. Half-life (t1/2)

D. Bioequivalence ratio (E)

Correct Answer: Bioequivalence ratio (E)

Question 3 of 5

Nonionic surface-active agents used as synthetic emulsifiers include

A. Tragacanth

B. Sodium lauryl sulphate

C. Sorbitan esters (spans)

D. None listed

Correct Answer: Sorbitan esters (spans)

Question 4 of 5

The following antiemetic is incorrectly matched to its mechanism of action?

A. Metoclopramide: Dopamine antagonist

B. Ondansetron: Serotonin agonist

C. Diphenhydramine: Antihistamine

D. Scopolamine: Muscarinic antagonist

Correct Answer: Ondansetron: Serotonin agonist

Question 5 of 5

The following inhibit at least one of the hepatic CYP450 isoenzymes:

A. Fluvoxamine

B. Grapefruit juice

C. Digoxin

D. Itraconazole

Correct Answer: Grapefruit juice

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