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HESI LPN · HESI LPN Medical Surgical Nursing · HESI The Hematologic System ATI

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Several gene mutations have been associated with juvenile myelomonocytic leukemia (JMML), and they may or may not have prognostic implications. A gene expression–based classification system has been found to be an independent predictor of clinical outcome in these patients. What is the disease signature that predicts a poor outcome?

A. Tyrosine kinase inhibitors
B. Acute myeloid leukemia–like
C. Chronic myeloid leukemia-like
D. BRAF pathway abnormalities

Expert Explanatory Rationale

Correct Answer: Acute myeloid leukemia–like

Question 2 of 5

A client is having a radioisotopic imaging scan. What action by the nurse is most important?

A. Assess the client for shellfish allergies.
B. Place the client on radiation precautions.
C. Sedate the client before the scan.
D. Teach the client about the procedure.

Expert Explanatory Rationale

Correct Answer: Teach the client about the procedure.

Question 3 of 5

The nurse is concerned that a patient is demonstrating signs of red blood cell production. What laboratory value did the nurse most likely use to make this decision?

A. Iron
B. Bilirubin
C. Thrombin
D. Intrinsic factor

Expert Explanatory Rationale

Correct Answer: Bilirubin

Question 4 of 5

An 18-year old male patient presents with bruising, fatigue, and diffuse extremity pain. He is noted to be tachypneic and hypoxic and has a diffuse interstitial infiltrate on chest x-ray. CBC reveals a WBC count of 285,000/mm3 (85% myeloblasts, with monocytic morphology), hemoglobin of 7.9 g/dL, and platelet count of 36,000/mm3. What is the most likely cause of the infiltrate and respiratory symptoms and the most appropriate initial treatment?

A. Hyperleukocytosis; initiation of induction chemotherapy
B. Hyperleukocytosis; leukapheresis or manual exchange transfusion and initiation of induction chemotherapy
C. COVID-19 infection; convalescent plasma and prednisone
D. Pneumococcal pneumonia; vancomycin

Expert Explanatory Rationale

Correct Answer: Hyperleukocytosis; leukapheresis or manual exchange transfusion and initiation of induction chemotherapy

Question 5 of 5

Plat. Transfusion is not indicated in:

A. aplastic an.
B. uraemia with bleeding
C. DIC
D. immunogenic thrombocytopenia

Expert Explanatory Rationale

Correct Answer: immunogenic thrombocytopenia

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