ATI RN · Obstetrics and Pediatrics · Pediatric Immune Disorder Test Questions
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A 40-day-old, previously healthy, fullterm female infant manifests fever, lethargy, and poor feeding for 12 hours. Physical examination reveals a lethargic child with vital signs of RR 70, HR 185, BP mean 25, T 39.50°C. The peripheral perfusion is poor, the chest reveals retractions, the abdomen is soft and reveals persistence of the umbilical cord, and the extremities are cool. Laboratory studies reveal a white blood cell count of 65,000 and a platelet count of 105,000. Family history reveals that a male sibling died suddenly at the age of 2 months, 10 years prior to the birth of this child. The most likely diagnosis is
Expert Explanatory Rationale
Correct Answer: leukocyte adhesion deficiency
In the alternative complement pathway, this component molecule undergoes spontaneous activation, which creates a challenge for organ xenotransplantation.
Expert Explanatory Rationale
Correct Answer: C3
The response time to antigenic stimulation for memory B and T cells is described as ___, for naïve B and T cells is described as ___, and for effector B and T cells is described as ___
Expert Explanatory Rationale
Correct Answer: Fast; Slow; Responding
IFN-γ stimulates ___ immunity by enhancing ___ T cells as well as activating macrophages and natural killer cells. IL-4/IL-5 stimulate ___ immunty (antibodies) by activating B cells and eosinophils and induce ___-type responses.
Expert Explanatory Rationale
Correct Answer: Cell-mediated; CD4+; Humoral; IgE
Which of the following types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells?
Expert Explanatory Rationale
Correct Answer: B cell
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