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ATI RN · Obstetrics and Pediatrics · Pediatric Immune Disorder Test Questions

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

A 40-day-old, previously healthy, fullterm female infant manifests fever, lethargy, and poor feeding for 12 hours. Physical examination reveals a lethargic child with vital signs of RR 70, HR 185, BP mean 25, T 39.50°C. The peripheral perfusion is poor, the chest reveals retractions, the abdomen is soft and reveals persistence of the umbilical cord, and the extremities are cool. Laboratory studies reveal a white blood cell count of 65,000 and a platelet count of 105,000. Family history reveals that a male sibling died suddenly at the age of 2 months, 10 years prior to the birth of this child. The most likely diagnosis is

A. chronic granulomatous disease
B. congenital leukemia
C. Kostmann syndrome
D. leukocyte adhesion deficiency

Expert Explanatory Rationale

Correct Answer: leukocyte adhesion deficiency

Question 2 of 5

In the alternative complement pathway, this component molecule undergoes spontaneous activation, which creates a challenge for organ xenotransplantation.

A. C1
B. C2
C. C3
D. C4

Expert Explanatory Rationale

Correct Answer: C3

Question 3 of 5

The response time to antigenic stimulation for memory B and T cells is described as ___, for naïve B and T cells is described as ___, and for effector B and T cells is described as ___

A. Slow; Fast; Responding
B. Fast; Slow; Responding
C. Responding; Slow; Fast
D. Responding; Fast; Slow

Expert Explanatory Rationale

Correct Answer: Fast; Slow; Responding

Question 4 of 5

IFN-γ stimulates ___ immunity by enhancing ___ T cells as well as activating macrophages and natural killer cells. IL-4/IL-5 stimulate ___ immunty (antibodies) by activating B cells and eosinophils and induce ___-type responses.

A. Cell-mediated; CD8+; Humoral; IgE
B. Cell-mediated; CD4+; Humoral; IgE
C. Cell-mediated; CD8+; Humoral; IgM
D. Cell-mediated; CD4+; Humoral; IgM

Expert Explanatory Rationale

Correct Answer: Cell-mediated; CD4+; Humoral; IgE

Question 5 of 5

Which of the following types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells?

A. Macrophage
B. Dendritic cell
C. B cell
D. None of the above

Expert Explanatory Rationale

Correct Answer: B cell

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