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ATI RN · ATI Medical Surgical · Hematological System

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

The patient is a 6-year-old boy referred to a hematologist for thrombocytopenia. He has no bleeding history or family history of bleeding. His only other past medical history is mild high-frequency hearing loss. What gene is responsible for these findings?

A. NBEAL2
B. GP-1Ba
C. MYH9
D. Deletions of long arm of chromosome 11

Expert Explanatory Rationale

Correct Answer: MYH9

Question 2 of 5

You examine a 10-year-old boy with severe aplastic anemia. He has no dysmorphic features and is at the 50th percentile for height and weight. Family history includes a sister with aplastic anemia unresponsive to anti-human thymocyte globulin (ATG) and cyclosporine who died early in the course of an unrelated donor hematopoietic stem cell transplant complicated by severe mucositis and transplant-related organ toxicities. There are no other siblings. A cousin died of acute myeloid leukemia at age 5 years. A peripheral blood sample test for Fanconi anemia is negative with no increased chromosomal breaks in response to diepoxybutane or mitomycin C. Which of the following is the most important next step in management?

A. Administer ATG and cyclosporine.
B. Search for a donor for matched unrelated transplant.
C. Send a bone marrow aspirate for Fanconi anemia testing.
D. Send a skin fibroblast culture for Fanconi anemia testing.

Expert Explanatory Rationale

Correct Answer: Send a skin fibroblast culture for Fanconi anemia testing.

Question 3 of 5

A 9-year-old child with osteosarcoma is being admitted for cisplatin therapy. What is the best regimen for prevention of chemotherapy-induced nausea and vomiting (CINV)?

A. Palonosetron and olanzapine
B. Dexamethasone and арrepitant
C. Granisetron, dexamethasone at 50% dosing, and арrepitant
D. Granisetron, dexamethasone at 100% dosing, and арrepitant

Expert Explanatory Rationale

Correct Answer: Granisetron, dexamethasone at 50% dosing, and арrepitant

Question 4 of 5

Gum bleeding is characteristic of all except:

A. chronic phenytoin therapy
B. aplastic an.
C. scurvy
D. haemophilia

Expert Explanatory Rationale

Correct Answer: chronic phenytoin therapy

Question 5 of 5

The vector of visceral leishmaniasis has geographical variations. In the Asian region, the main vector is

A. Phlebotomus species
B. Lutzomyia species
C. Anopheles species
D. Mansonia species

Expert Explanatory Rationale

Correct Answer: Phlebotomus species

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