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ATI LPN · ATI Pharmacology · Basic Pharmacological Principles

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Showing all 5 practice questions with expert explanatory rationales.

Question 1 of 5

Which drug is contraindicated in patients with a history of angioedema?

A. Beta-blockers

B. ACE inhibitors

C. Diuretics

D. Nitrates

Expert Explanatory Rationale

Correct Answer: ACE inhibitors

Question 2 of 5

A patient wants to know about the possible interactions of the various drugs that he has been prescribed for an illness. The nurse explains that the drugs interact with each other and produce an effect that is greater than the sum of their separate actions. Which of the following reactions is the nurse informing about?

A. Additive drug reaction

B. Synergistic drug reaction

C. Antagonistic drug reaction

D. Toxic drug reaction

Expert Explanatory Rationale

Correct Answer: Synergistic drug reaction

Question 3 of 5

Which of the following processes in the kidney can result in retention of a drug in the body?

A. Glomerular filtration

B. Active tubular secretion

C. Passive tubular diffusion

D. All of the above

Expert Explanatory Rationale

Correct Answer: Passive tubular diffusion

Question 4 of 5

Which of the following statements is true regarding the therapeutic index (TI) of a drug?

A. A drug with a large TI is more dangerous than a drug with a small TI.

B. The formula for TI is ED50 / LD50.

C. ED50 is 50% of the effective clinical dose.

D. TI is the ratio of the median lethal dose to the median effective dose.

Expert Explanatory Rationale

Correct Answer: TI is the ratio of the median lethal dose to the median effective dose.

Question 5 of 5

A student nurse has completed an initial pharmacology course and tells a nurse that it was difficult. What is the best response by the nurse?

A. It may be over, but now you must apply what you have learned to patient care.

B. Learning is gradual and continuous; we never completely master all areas of pharmacology.

C. Learning is always painful, but we must continue anyway.

D. It really isn't over; you should take a graduate course next.

Expert Explanatory Rationale

Correct Answer: Learning is gradual and continuous; we never completely master all areas of pharmacology.

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